Beta-glucan peptide (BGP)InvivoGen Kontakt z doradcą
Beta-glucan peptide (BGP) is a high molecular weight (~100 kDa) polysaccharide extracted from the fungus Trametes versicolor.
BGP consists of a highly ramified glucan portion, comprising a beta 1-4 main chain and beta 1-3 side chain, with beta 1-6 side chains covalently linked to a polypeptide portion rich in aspartic, glutamic and other amino acids.
BGP activates murine macrophages and HEK-Blue™ Dectin-1 cells. Detection of β-glucans by Dectin-1 receptor leads to the CARD9-dependent activation of NF-κB and MAP kinases.