ATP

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NLRP3 Inflammasome Inducer - Adenosine 5'-triphosphate disodium salt
ATP

Adenosine triphosphate (ATP), a potassium efflux agent, can trigger the activation of NLRP3 inflammasome in response to PAMPs, such as LPS and peptidoglycan.

It stimulates the caspase-1-dependent cleavage and secretion of IL-1β from LPS-stimulated cells.

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