Poly(I:C) (HMW) RhodamineInvivoGen Kontakt z doradcą
Poly(I:C) Rhodamine was chemically labeled by covalent coupling of a rhodamine probe containing a reactive alkylating group. This confers fluorescent properties to poly(I:C) (HMW) whilst retaining TLR3 recognition properties.
Polyinosinic-polycytidylic acid (poly(I:C)) is a synthetic analog of double stranded RNA (dsRNA), a molecular pattern associated with viral infection.
Both natural and synthetic dsRNAs are known to induce type I interferons (IFN) and other cytokines production.
Poly(I:C) is recognized by Toll-like receptor 3 (TLR3).