ODN 2006 Biotin

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TLR9 Agonist - Biotin-labelled CpG ODN 2006, Class B, Human-preferred
ODN 2006 Biotin

CpG   ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs).

These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.

They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.

ODN  2006 Biotin is a B-class CpG ODN with a preference for human TLR9.

ODN 2006 Biotin  can  be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.

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