ODN 2006 BiotinInvivoGen Kontakt z doradcą
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs).
These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.
They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.
ODN 2006 Biotin is a B-class CpG ODN with a preference for human TLR9.
ODN 2006 Biotin can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.