ODN 2006 FITC

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TLR9 Agonist - FITC-labelled CpG ODN 2006, Class B, Human-preferred
ODN 2006 FITC

ODN 2006 FITC is a CpG ODN class B with a preference for human TLR9.

ODN 2006 FITC can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.

CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs).

These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.

They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.

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