ODN 2395 FITC

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TLR9 Agonist - FITC-labelled CpG ODN 2395, Class C, Human/Mouse-preferred
ODN 2395 FITC

CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA.

They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules.

ODN 2395 FITC is a C-class CpG ODN specific for human / mouse TLR9. ODN 2395 FITC can  be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.

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