hPD-L1-Fc is a soluble human PD-L1 (CD274) fusion protein generated by fusing the N-terminal extracellular domain of human PD-L1 (aa 19-237) to the N-terminus of an engineered human IgG1 Fc domain with a 2 amino acid linker.
hPD-L1-Fc has an apparent molecular weight of ~66 kDa on an SDS‑PAGE gel.
hPD‑L1‑Fc is expressed in CHO cells and purified by protein G affinity chromatography.