Fc-hDectin-1a is a soluble human Dectin-1 receptor constructed by fusing the C-terminal extracellular domain of human Dectin-1a (aa 67-247) to the C-terminus of an engineered human IgG1 Fc domain with a 10 amino acid linker.
Fc-hDectin-1a has an apparent molecular weight of ~55 kDa on SDS-PAGE.
Fc-hDectin-1a is expressed in CHO cells and purified by protein G affinity chromatography.