PRR Signaling Genes

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PRR Signaling Genes

Products

  • AAMP: Angio associated migratory cell protein
  • ACT1 (TRAF3IP2): TRAF3 interacting protein 2
  • AGER: Advanced glycosylation end product-specific receptor
  • AHR: Aryl hydrocarbon receptor
  • AIRE: Autoimmune regulator
  • AKT1: AKT serine/threonine kinase 1
  • ARF6: ADP-ribosylation factor 6
  • ARHGEF2: Rho/Rac guanine nucleotide exchange factor 2
  • ASC: Apoptosis-associated speck-like protein containing a CARD
  • BECN1: Beclin 1
  • BTK: Bruton agammaglobulinemia tyrosine kinase
  • CARD 6: Caspase recruitment domain family member 6
  • CARD 8: Caspase recruitment domain family member 8
  • CARD 9: Caspase recruitment domain family member 9
  • CARD11: Caspase recruitment domain family member 11
  • CD 14: CD14 molecule
  • CD148: CD148 molecule
  • CD300LF: CD300 molecule like family member F
  • CNKSR1: Connector enhancer of kinase suppressor of ras 1
  • CSNK2A1: Casein kinase 2 alpha 1
  • DAP12 (TYROBP): Transmembrane immune signaling adaptor TYROBP
  • DDX3X: DEAD box helicase 3 X-linked
  • DDX60: DExD/H-box helicase 60
  • DOK3: Docking protein 3
  • ENPP1: Ectonucleotide pyrophosphatase/phosphodiesterase 1
  • FADD: Fas associated via death domain
  • G3BP1: G3BP stress granule assembly factor 1
  • GAS6: Growth arrest specific 6
  • GBP2: Guanylate binding protein 2
  • GFI1: Growth factor independent 1 transcription repressor
  • GRN: Granulin
  • GRP94: Heat shock protein 90 beta family member 1
  • HIGD1A: HIG1 hypoxia inducible domain family member 1A
  • HSPB8: Heat shock protein family B (small) member 8
  • IFIT3: Interferon-induced protein with tetratricopeptide repeats 3
  • IKKα: IKK-alpha
  • IKKα-HA: IKK-alpha, HA-tagged
  • IKKβ: IKK-beta
  • IKKβ-HA: IKK-beta, HA-tagged
  • IKKε: IKK-epsilon
  • IPS1: Interferon-beta promoter stimulator 1
  • IRAK1: IL-1R associated kinase 1
  • IRAK1-HA: IL-1R associated kinase 1, HA-tagged
  • IRAK4: IL-1R associated kinase 4
  • IRF1: Interferon Regulatory Factor 1
  • IRF3: Interferon Regulatory Factor 3
  • IRF3-HA: Interferon Regulatory Factor 3, HA-tagged
  • IRF5: Interferon Regulatory Factor 5
  • IRF5-HA: Interferon Regulatory Factor 5, HA-tagged
  • IRF7: Interferon Regulatory Factor 7
  • IRF7-HA: Interferon Regulatory Factor 7, HA-tagged
  • IRF8: Interferon Regulatory Factor 8
  • IRF9: Interferon Regulatory Factor 9 
  • IRF9-HA: Interferon Regulatory Factor 9, HA-tagged
  • ITCH: Itchy E3 ubiquitin protein ligase
  • KSR1: Kinase suppressor of ras 1
  • LBP: Lipopolysaccharide-binding protein
  • LRRC59: Leucine rich repeat containing 59
  • LRRFIP2: LRR binding FLII interacting protein 2
  • LSP1: Lymphocyte specific protein 1
  • MAP2K2: Mitogen-activated protein kinase kinase 2
  • MAP3K3: Mitogen-activated protein kinase kinase kinase 3
  • MAP3K7 (TAK1): Mitogen-activated protein kinase kinase kinase 7
  • MAPK1: Mitogen-activated protein kinase 1
  • MD1: Myeloid differentiation factor 1
  • MD2: Myeloid differentiation factor 2
  • MDA5 (IFIH1): Melanoma differentiation-associated gene 5
  • MINT3: Munc-18-1-interacting protein 3
  • MSK1: Ribosomal protein S6 kinase A5
  • MSK2: Ribosomal protein S6 kinase A4
  • MyD88: Myeloid Differentiation Primary Response  88
  • MyD88-HA: Myeloid Differentiation primary response gene 88, HA-tagged
  • NAIP1: NLR family, apoptosis inhibitory protein 1
  • NAIP5: NLR family, apoptosis inhibitory protein 5
  • NAP1: NAK-associated protein 1
  • NEMO: NF-kappaB Essential Modulator
  • NEMO-HA: NF-kappaB Essential Modulator, HA-tagged
  • NIBP: NIK and IKK(beta) binding protein
  • NLRC5: NLR family, CARD domain containing 5
  • NMU: Neuromedin U
  • NMUR1: Neuromedin U receptor 1
  • OLR1 (LOX1): Oxidized low density lipoprotein receptor 1
  • OTUD5: OTU deubiquitinase 5
  • PARP13: Poly(ADP-ribose) polymerase 13
  • pDUO-CD14/TLR2 pDUO: plasmid co-expressing CD14 and TLR2 genes
  • pDUO-CD14/TLR4 pDUO: plasmid co-expressing CD14 and TLR4 genes
  • pDUO-MD1/RP105 pDUO: plasmid co-expressing MD1 and RP105 genes
  • pDUO-MD2/TLR4 pDUO: plasmid co-expressing MD2 and TLR4 genes
  • pDUO-TLR1/TLR2 pDUO: plasmid co-expressing TLR1 and TLR2 genes
  • pDUO2-MD2/CD14 pDUO2: plasmid co-expressing MD2 and CD14 genes
  • Pellino1: Pellino 1
  • Pellino2: Pellino 2
  • Pellino3: Pellino 3
  • PIKFYVE: Phosphoinositide kinase, FYVE finger containing
  • PKR: Protein kinase, interferon-inducible double stranded RNA dependent.
  • PLCG2: Phospholipase C gamma 2 (phosphatidylinositol-specific)
  • PPP3CA: Calcineurin A alpha 
  • PPP3CB: Calcineurin Alpha 2
  • PPP3R1: Calcineurin Beta
  • PRAT4A: Protein Associated with TLR4, A
  • PRAT4B: Protein Associated with TLR4, B
  • PRKD1: Protein kinase D1
  • PRKRA: Protein activator of interferon induced protein kinase EIF2AK2
  • PROS1: Protein S
  • PYDC1: Pyrin domain containing 1
  • PYDC2: Pyrin domain containing 2 
  • PYDC4: Pyrin domain containing 4
  • RAB 8A: RAB8A, member RAS oncogene family
  • RAB11A: RAB11A, member RAS oncogene family
  • RAC1: Rac family small GTPase 1
  • RAF1: Raf-1 proto-oncogene, serine/threonine kinase
  • RHBDF2: Rhomboid 5 homolog 2
  • RIOK3: RIO kinase 3
  • RIPK1: Receptor interacting serine/threonine kinase 1
  • RIPK2: Receptor interacting serine/threonine kinase 2
  • RIPK3: Receptor interacting serine/threonine kinase 3
  • RNF166: Ring finger protein 166
  • SARM1: Sterile alpha and TIR motif containing 1
  • SIRPB1: Signal regulatory protein beta 1
  • SIRPG: Signal regulatory protein gamma
  • SLAMF1 (CD150): Signaling lymphocytic activation molecule family member 1
  • SLC15A4: Solute carrier family 15 member 4
  • SLC19A1: Solute carrier family 19 member 1
  • STAP2: Signal transducing adaptor family member 2
  • STEEP1: STING1 ER exit protein 1
  • STING: human STING gene, "wild type"
  • STING-A162: human STING gene, S162A variant
  • STING-A230: human STING gene, G230A variant
  • STING-Gt: mouse STING gene, I199N "Goldenticket (Gt)" variant 
  • STING-H232: human STING gene, R232H variant
  • STING-HA: human STING gene, "wild type", HA-tagged
  • STING-HAQ: human STING gene, R71H-G230A-R293Q variant
  • STING-M155: human STING gene, V155M variant 
  • STING-MRP: human STING gene, isoform lacking exon 7
  • STING-N200: human STING gene, I200N variant
  • STING-ß: human STING gene, isoform lacking exons 1-5
  • STING-S154: human STING gene, N154S variant 
  • SUGT1: SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
  • SYK: Spleen tyrosine kinase
  • TAB1: TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  • TAB2: TGF-beta activated kinase 1 (MAP3K7) binding protein 2
  • TAB3: TGF-beta activated kinase 1 (MAP3K7) binding protein 3
  • TANK: TRAF family member-associated NFKB activator
  • TASL: TLR adaptor interacting with SLC15A4 on the lysosome
  • TBK1: TANK Binding Kinase 1
  • TBKBP1: TBK1 binding protein 1
  • TIFA: TRAF interacting protein with a forkhead associated domain
  • TIRAP: TIR domain containing adaptor protein
  • TLR-Related Dominant Negative Genes: Dominant negative engineered TLR signaling genes
  • TMED 2: Transmembrane p24 trafficking protein 2
  • TMED10: Transmembrane p24 trafficking protein 10
  • TOMM70A: Translocase of outer mitochondrial membrane 70
  • TRADD: TNFRSF1A associated via death domain
  • TRAF3: TNF receptor associated factor 3
  • TRAF6: TNF receptor associated factor 6
  • TRAF6-HA: TNF receptor-associated factor 6, HA-tagged
  • TRAM (TICAM2): TRIF-related adapter molecule
  • TRIF (TICAM1): TIR domain-containing adapter inducing IFNβ
  • TRIL: TLR4 interactor with leucine rich repeats
  • TRIM13: Tripartite motif containing 13
  • TRIM22: Tripartite motif containing 22
  • TRIM23: Tripartite motif containing 23
  • TRIM25: Tripartite motif containing 25
  • TRIM26: Tripartite motif containing 26
  • TRIM27: Tripartite motif containing 27
  • TRIM32: Tripartite motif containing 32
  • TRIM38: Tripartite motif containing 38
  • TRIM56: Tripartite motif containing 56
  • UNC93B1: Unc-93 homolog B1
  • USP7: Ubiquitin specific peptidase 7
  • WDFY1: WD repeat and FYVE domain containing 1
  • XIAP: X-linked inhibitor of apoptosis
  • ZDHHC1: Zinc finger DHHC-type containing 1

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