PRR Signaling Genes

Products

• AAMP: Angio associated migratory cell protein
• ACT1 (TRAF3IP2): TRAF3 interacting protein 2
• AGER: Advanced glycosylation end product-specific receptor
• AHR: Aryl hydrocarbon receptor
• AIRE: Autoimmune regulator
• AKT1: AKT serine/threonine kinase 1
• ARF6: ADP-ribosylation factor 6
• ARHGEF2: Rho/Rac guanine nucleotide exchange factor 2
• ASC: Apoptosis-associated speck-like protein containing a CARD
• BECN1: Beclin 1
• BTK: Bruton agammaglobulinemia tyrosine kinase
• CARD 6: Caspase recruitment domain family member 6
• CARD 8: Caspase recruitment domain family member 8
• CARD 9: Caspase recruitment domain family member 9
• CARD11: Caspase recruitment domain family member 11
• CD 14: CD14 molecule
• CD148: CD148 molecule
• CD300LF: CD300 molecule like family member F
• CNKSR1: Connector enhancer of kinase suppressor of ras 1
• CSNK2A1: Casein kinase 2 alpha 1
• DAP12 (TYROBP): Transmembrane immune signaling adaptor TYROBP
• DDX3X: DEAD box helicase 3 X-linked
• DDX60: DExD/H-box helicase 60
• DOK3: Docking protein 3
• ENPP1: Ectonucleotide pyrophosphatase/phosphodiesterase 1
• FADD: Fas associated via death domain
• G3BP1: G3BP stress granule assembly factor 1
• GAS6: Growth arrest specific 6
• GBP2: Guanylate binding protein 2
• GFI1: Growth factor independent 1 transcription repressor
• GRN: Granulin
• GRP94: Heat shock protein 90 beta family member 1
• HIGD1A: HIG1 hypoxia inducible domain family member 1A
• HSPB8: Heat shock protein family B (small) member 8
• IFIT3: Interferon-induced protein with tetratricopeptide repeats 3
• IKKα: IKK-alpha
• IKKα-HA: IKK-alpha, HA-tagged
• IKKβ: IKK-beta
• IKKβ-HA: IKK-beta, HA-tagged
• IKKε: IKK-epsilon
• IPS1: Interferon-beta promoter stimulator 1
• IRAK1: IL-1R associated kinase 1
• IRAK1-HA: IL-1R associated kinase 1, HA-tagged
• IRAK4: IL-1R associated kinase 4
• IRF1: Interferon Regulatory Factor 1
• IRF3: Interferon Regulatory Factor 3
• IRF3-HA: Interferon Regulatory Factor 3, HA-tagged
• IRF5: Interferon Regulatory Factor 5
• IRF5-HA: Interferon Regulatory Factor 5, HA-tagged
• IRF7: Interferon Regulatory Factor 7
• IRF7-HA: Interferon Regulatory Factor 7, HA-tagged
• IRF8: Interferon Regulatory Factor 8
• IRF9: Interferon Regulatory Factor 9 
• IRF9-HA: Interferon Regulatory Factor 9, HA-tagged
• ITCH: Itchy E3 ubiquitin protein ligase
• KSR1: Kinase suppressor of ras 1
• LBP: Lipopolysaccharide-binding protein
• LRRC59: Leucine rich repeat containing 59
• LRRFIP2: LRR binding FLII interacting protein 2
• LSP1: Lymphocyte specific protein 1
• MAP2K2: Mitogen-activated protein kinase kinase 2
• MAP3K3: Mitogen-activated protein kinase kinase kinase 3
• MAP3K7 (TAK1): Mitogen-activated protein kinase kinase kinase 7
• MAPK1: Mitogen-activated protein kinase 1
• MD1: Myeloid differentiation factor 1
• MD2: Myeloid differentiation factor 2
• MDA5 (IFIH1): Melanoma differentiation-associated gene 5
• MINT3: Munc-18-1-interacting protein 3
• MSK1: Ribosomal protein S6 kinase A5
• MSK2: Ribosomal protein S6 kinase A4
• MyD88: Myeloid Differentiation Primary Response  88
• MyD88-HA: Myeloid Differentiation primary response gene 88, HA-tagged
• NAIP1: NLR family, apoptosis inhibitory protein 1
• NAIP5: NLR family, apoptosis inhibitory protein 5
• NAP1: NAK-associated protein 1
• NEMO: NF-kappaB Essential Modulator
• NEMO-HA: NF-kappaB Essential Modulator, HA-tagged
• NIBP: NIK and IKK(beta) binding protein
• NLRC5: NLR family, CARD domain containing 5
• NMU: Neuromedin U
• NMUR1: Neuromedin U receptor 1
• OLR1 (LOX1): Oxidized low density lipoprotein receptor 1
• OTUD5: OTU deubiquitinase 5
• PARP13: Poly(ADP-ribose) polymerase 13
• pDUO-CD14/TLR2 pDUO: plasmid co-expressing CD14 and TLR2 genes
• pDUO-CD14/TLR4 pDUO: plasmid co-expressing CD14 and TLR4 genes
• pDUO-MD1/RP105 pDUO: plasmid co-expressing MD1 and RP105 genes
• pDUO-MD2/TLR4 pDUO: plasmid co-expressing MD2 and TLR4 genes
• pDUO-TLR1/TLR2 pDUO: plasmid co-expressing TLR1 and TLR2 genes
• pDUO2-MD2/CD14 pDUO2: plasmid co-expressing MD2 and CD14 genes
• Pellino1: Pellino 1
• Pellino2: Pellino 2
• Pellino3: Pellino 3
• PIKFYVE: Phosphoinositide kinase, FYVE finger containing
• PKR: Protein kinase, interferon-inducible double stranded RNA dependent.
• PLCG2: Phospholipase C gamma 2 (phosphatidylinositol-specific)
• PPP3CA: Calcineurin A alpha 
• PPP3CB: Calcineurin Alpha 2
• PPP3R1: Calcineurin Beta
• PRAT4A: Protein Associated with TLR4, A
• PRAT4B: Protein Associated with TLR4, B
• PRKD1: Protein kinase D1
• PRKRA: Protein activator of interferon induced protein kinase EIF2AK2
• PROS1: Protein S
• PYDC1: Pyrin domain containing 1
• PYDC2: Pyrin domain containing 2 
• PYDC4: Pyrin domain containing 4
• RAB 8A: RAB8A, member RAS oncogene family
• RAB11A: RAB11A, member RAS oncogene family
• RAC1: Rac family small GTPase 1
• RAF1: Raf-1 proto-oncogene, serine/threonine kinase
• RHBDF2: Rhomboid 5 homolog 2
• RIOK3: RIO kinase 3
• RIPK1: Receptor interacting serine/threonine kinase 1
• RIPK2: Receptor interacting serine/threonine kinase 2
• RIPK3: Receptor interacting serine/threonine kinase 3
• RNF166: Ring finger protein 166
• SARM1: Sterile alpha and TIR motif containing 1
• SIRPB1: Signal regulatory protein beta 1
• SIRPG: Signal regulatory protein gamma
• SLAMF1 (CD150): Signaling lymphocytic activation molecule family member 1
• SLC15A4: Solute carrier family 15 member 4
• SLC19A1: Solute carrier family 19 member 1
• STAP2: Signal transducing adaptor family member 2
• STEEP1: STING1 ER exit protein 1
• STING: human STING gene, "wild type"
• STING-A162: human STING gene, S162A variant
• STING-A230: human STING gene, G230A variant
• STING-Gt: mouse STING gene, I199N "Goldenticket (Gt)" variant 
• STING-H232: human STING gene, R232H variant
• STING-HA: human STING gene, "wild type", HA-tagged
• STING-HAQ: human STING gene, R71H-G230A-R293Q variant
• STING-M155: human STING gene, V155M variant 
• STING-MRP: human STING gene, isoform lacking exon 7
• STING-N200: human STING gene, I200N variant
• STING-ß: human STING gene, isoform lacking exons 1-5
• STING-S154: human STING gene, N154S variant 
• SUGT1: SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
• SYK: Spleen tyrosine kinase
• TAB1: TGF-beta activated kinase 1 (MAP3K7) binding protein 1
• TAB2: TGF-beta activated kinase 1 (MAP3K7) binding protein 2
• TAB3: TGF-beta activated kinase 1 (MAP3K7) binding protein 3
• TANK: TRAF family member-associated NFKB activator
• TASL: TLR adaptor interacting with SLC15A4 on the lysosome
• TBK1: TANK Binding Kinase 1
• TBKBP1: TBK1 binding protein 1
• TIFA: TRAF interacting protein with a forkhead associated domain
• TIRAP: TIR domain containing adaptor protein
• TLR-Related Dominant Negative Genes: Dominant negative engineered TLR signaling genes
• TMED 2: Transmembrane p24 trafficking protein 2
• TMED10: Transmembrane p24 trafficking protein 10
• TOMM70A: Translocase of outer mitochondrial membrane 70
• TRADD: TNFRSF1A associated via death domain
• TRAF3: TNF receptor associated factor 3
• TRAF6: TNF receptor associated factor 6
• TRAF6-HA: TNF receptor-associated factor 6, HA-tagged
• TRAM (TICAM2): TRIF-related adapter molecule
• TRIF (TICAM1): TIR domain-containing adapter inducing IFNβ
• TRIL: TLR4 interactor with leucine rich repeats
• TRIM13: Tripartite motif containing 13
• TRIM22: Tripartite motif containing 22
• TRIM23: Tripartite motif containing 23
• TRIM25: Tripartite motif containing 25
• TRIM26: Tripartite motif containing 26
• TRIM27: Tripartite motif containing 27
• TRIM32: Tripartite motif containing 32
• TRIM38: Tripartite motif containing 38
• TRIM56: Tripartite motif containing 56
• UNC93B1: Unc-93 homolog B1
• USP7: Ubiquitin specific peptidase 7
• WDFY1: WD repeat and FYVE domain containing 1
• XIAP: X-linked inhibitor of apoptosis
• ZDHHC1: Zinc finger DHHC-type containing 1