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Blasticidin

Blasticidin is an efficient selective antibiotic that acts on both eukaryotic and prokaryotic cells. Blasticidin is a peptidyl nucleoside antibiotic isolated from Streptomyces griseochromogenes that inhibits protein synthesis by interfering with the peptide-bond formation in the ribosomal machinery.

Numer kat. Produkt Opakowanie Opis
ant-bl-01 Blasticidin (solution) 100 mg (10 x 1 ml) Selective antibiotic for the bsr gene
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ant-bl-05 Blasticidin (solution) 500 mg (50 x 1 ml) Selective antibiotic for the bsr gene
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ant-bl-05b Blasticidin (solution) 500 mg (50ml bottle) Selective antibiotic for the bsr gene
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ant-bl-10p Blasticidin (Powder) 1g Selective antibiotic for the bsr gene
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OPIS

Resistance to blasticidin is conferred by the blasticidin resistance gene from Bacillus cereus (bsr), which codes for blasticidin-S deaminase.

Cell death induced by blasticidin is rapid and cell lines carrying a blasticidin resistance gene can be obtained in less than a week. Typically, mammalian cells are sensitive to blasticidin concentrations of 1-10 µg/ml, and bacteria to 25-100 µg/ml.

Product concentration: 10 mg/ml
Quality Control: Each lot is thoroughly tested to ensure the absence of lot-to-lot variation.
Purity: ≥ 95% (HPLC)
Endotoxin level: < 1 EU/mg
Physicochemical characterization: pH, appearance
Cell-culture tested: potency validated in blasticidin-sensitive and blasticidin-resistant mammalian cell lines
Non-cytotoxicity of trace contaminants: absence of long-term effects confirmed in blasticidin-resistant cells

DO POBRANIA

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