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Puromycin

Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It specifically inhibits peptidyl transfer on both prokaryotic and eukaryotic ribosomes.

Numer kat. Produkt Opakowanie Opis
ant-pr-1 Puromycin (solution) 100 mg (10 x 1 ml) Selective antibiotic for the Pac gene
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ant-pr-5 Puromycin (solution) 500 mg (50 x 1 ml) Selective antibiotic for the Pac gene
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ant-pr-5b Puromycin (solution) 500 mg (1 x 50 ml) Selective antibiotic for the Pac gene
Dodaj do Koszyka Zapytań (możesz wybrać kilka produktów) lub napisz na alab@alab.com.pl

OPIS

This antibiotic inhibits the growth of Gram positive bacteria and various animal and insect cells. Puromycin can also be used in some particular conditions for the selection of E. coli transformants.
Resistance to puromycin is conferred by the Pac gene encoding a puromycin N-acetyl-transferase (PAC) that was found in a Streptomyces producer strain.

Animal cells are generally sensitive to concentrations from 1 to 10 µg/ml.

 

Product concentration: 10 mg/ml
CAS number: 58-58-2

Quality Control: Each lot is thoroughly tested to ensure the absence of lot-to-lot variation.
Purity:
≥ 98% (HPLC)
Endotoxin level:
< 5 EU/mg
Physicochemical characterization:
pH, appearance
Cell-culture tested:
potency validated in puromycin-sensitive and puromycin‑resistant mammalian cell lines
Non-cytotoxicity of trace contaminants:
absence of long-term effects confirmed in puromycin-resistant cells

 

Puromycin – Manufacturer’s Website

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