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Zeocin™

InvivoGen is the sole worldwide producer of Zeocin™, a popular and effective antibiotic for the selection of vectors bearing the Sh ble gene in a variety of cells types (bacteria, eukaryotic microorganisms, plant and animal cells).

 

Numer kat. Produkt Opakowanie Opis
ant-zn-1 Zeocin™ (solution) 1g (10 x 1 ml) Selective antibiotic for the Sh ble gene
Dodaj do Koszyka Zapytań (możesz wybrać kilka produktów) lub napisz na alab@alab.com.pl
ant-zn-5 Zeocin™ (solution) 5g (50 x 1 ml) Selective antibiotic for the Sh ble gene
Dodaj do Koszyka Zapytań (możesz wybrać kilka produktów) lub napisz na alab@alab.com.pl
ant-zn-5b Zeocin™ (solution) 5 g (50 ml bottle) Selective antibiotic for the Sh ble gene
Dodaj do Koszyka Zapytań (możesz wybrać kilka produktów) lub napisz na alab@alab.com.pl
ant-zn-1p Zeocin™ (powder) 1g Selective antibiotic for the Sh ble gene
Dodaj do Koszyka Zapytań (możesz wybrać kilka produktów) lub napisz na alab@alab.com.pl
ant-zn-5p Zeocin™ (powder) 5g Selective antibiotic for the Sh ble gene
Dodaj do Koszyka Zapytań (możesz wybrać kilka produktów) lub napisz na alab@alab.com.pl

OPIS

Resistance to Zeocin™ is conferred by the Sh ble gene product, which inactivates Zeocin™ by binding to the antibiotic. Sh ble is a small gene, only 370bp in size, carried in a number of InvivoGen’s vectors.

Zeocin™ is a copper-chelated glycopeptide antibiotic produced by Streptomyces CL990. Zeocin™ causes cell death by intercalating into DNA and cleaving it. The action of Zeocin™ is effective on most aerobic cells.

Typically, mammalian cells are sensitive to Zeocin™ concentrations of 50-400 µg/ml, and bacteria to 25 µg/ml.

Product concentration: 100 mg/ml in solution
CAS number: 11006-33-0

Quality Control: Each lot is thoroughly tested to ensure the absence of lot-to-lot variation.
Endotoxin level:
< 1 EU/mg
Physicochemical characterization:
HPLC, pH, appearance
Cell-culture tested:
potency validated in Zeocin™-sensitive and Zeocin™-resistant mammalian cell lines
Non-cytotoxicity of trace contaminants:
absence of long-term effects confirmed in Zeocin™-resistant cells

 

Zeocin™ – Manufacturer’s Website

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