ODN 2216 Biotin

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TLR9 Agonist - Biotin-labelled CpG ODN 2216, Class A, Human-preferred
ODN 2216 Biotin

CpG  ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs).

These CpG  motifs are present at a 20-fold greater frequency in bacterial DNA  compared to mammalian DNA. They have been shown to induce a coordinated  set of immune responses based on the activation of immune cells  primarily involved in the recognition of these molecules.

ODN 2216 Biotin is a A-class CpG ODN with a preference for human TLR9.

ODN 2216 Biotin can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.

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