Mouse IgG2a Control

Anti-β-Gal-mIgG2a InvivoFit™ is a recombinant monoclonal antibody (mAb) comprising the variable region of the hybridoma-derived mAb Mouse IgG2a Control (clone: T9C6) that targets E. coli β-galactosidase (β-Gal).

This mAb does not react with murine proteins.

Anti-β-Gal-mIgG2a InvivoFit™ features the murine IgG2a isotype, a major immunoglobin present in serum. This isotype displays very high ADCP, high ADCC and high CDC [1].

This mAb is provided as an isotype control for use with InvivoGen's IgG2a antibodies in the mouse anti-mouse mAbs collection.

It has been produced in CHO cells and purified by affinity chromatography with protein G.

Key features of Anti-β-Gal-mIgG2a InvivoFit™:

• Sequence is 100% murine
• Guaranteed sterile, endotoxin level < 1 EU/mg
• Suitable for parenteral delivery in mice (azide-free)
• Low aggregation < 5%
• Produced in both animal-free facilities and defined media

References:

1. Nimmerjahn F. et al., 2005. FcgammaRIV: a novel FcR with distinct IgG subclass specificity. Immunity. 2005 Jul;23(1):41-51.