Recombinant human IL-1β

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Recombinant Cytokine, source: E. coli
Recombinant human IL-1β

Interleukin 1 beta (IL-1β) is a secreted pro-inflammatory cytokine that participates in the generation of systemic and local responses to infection and injury. Human IL-1β is produced as a precursor (269 amino acids) that is cleaved intracellularly by the cysteine protease Caspase-1 to generate the active cytokine.

Recombinant human interleukin 1 beta (IL-1β) is a non-glycosylated polypeptide chain containing 153 amino acids with a molecular mass of 17000 Daltons. This recombinant cytokine is produced in Escherichia coli.

IL-1β is used to induce its cognate signalling pathway in HEK-Blue™ IL-1β cells.

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